The potential uses of large number of herbal drugs are limited due to their poor bioavailability and poor absorption. This limitation can be improved by formulating a appropriate drug delivery system, which enhance the rate and the extent of drug. Phytomedicines, complex chemical mixtures prepared from plants, have been used in medicine since ancient times and continue to have widespread popular use. The hydrophilic nature and unique chemical structure of these compounds pose major challenge because of their poor bioavailability through the skin or gut. The use of phytosomes is a novel formulation technology which helps to overcome these problems. Phytosomes are produced by a process whereby the standardized plant extract or its constituents are bound to phospholipids mainly phosphatidycholine producing a lipid compatible molecular complex. This phytosomes resembles a little cell. It is also often known as herbosomes. The phytosomes technology has been enhanced the bioavailability of many popular herbal extracts including milk thistle, Ginkgo biloba, grape seed , green tea, hawthorn, ginseng etc and can be developed for various therapeutic uses or a dietary supplements. Phytosome exhibit better pharmacokinetic and pharmacodynamic profile than conventional herbal extracts.
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